SCHEMBL689226

SCHEMBL689226

Nc1cccc(C(F)(c2cccc(N)c2O)C(F)(F)C(F)(F)F)c1O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.37
CA2 P00918 1/20 0.34
TSHR P16473 2/20 0.32
ALOX15 P16050 1/20 0.32
PDK2 Q15119 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19326634 0.94 MMP2 (0.36) MMP2CA2TSHRALOX15PDK2
SCHEMBL9617287 0.82 CD44 (0.38) TSHRALOX15PDK2SMN1; SMN2ALDH1A1
SCHEMBL30390082 0.80 MMP2 (0.39) MMP2CA2TSHRALOX15PDK2
SCHEMBL6757407 0.80 MMP2 (0.39) MMP2CA2TSHRALOX15PDK2
SCHEMBL6756206 0.79 MMP2 (0.42) MMP2CA2TSHRALOX15PDK2
SCHEMBL103733 0.79 MMP2 (0.42) MMP2CA2TSHRALOX15GABRA1
SCHEMBL1964819 0.79 SMN1; SMN2 (0.39) CA2TSHRALOX15PDK2SMN1; SMN2
SCHEMBL6004099 0.78 SMN1; SMN2 (0.38) TSHRALOX15PDK2SMN1; SMN2ALDH1A1
SCHEMBL9016041 0.77 CYP3A4 (0.48) TSHRSMN1; SMN2ALDH1A1CYP3A4HPGD
SCHEMBL6319546 0.77 TSHR (0.31) TSHRSMN1; SMN2ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3290461-B1 POLYIMIDE RESIN AND FILM USING SAME KOLON INC (KR) 2024-01-17 EP claimed
CN-107531902-B Polyimide resin and film using the same 可隆工业株式会社 2020-10-02 CN claimed
US-RE48141-E1 Transparent polyamide-imide resin and film using same KOLON INDUSTRIES, INC. (KR) 2020-08-04 US claimed
CN-107001629-B Resin and photosensitive polymer combination 东丽株式会社 2019-09-24 CN claimed
EP-3088440-B1 TRANSPARENT POLYAMIDE-IMIDE RESIN AND FILM USING SAME KOLON INC (KR) 2018-09-19 EP claimed
US-20180134848-A1 POLYIMIDE RESIN AND FILM USING SAME KOLON INDUSTRIES, INC. (KR) 2018-05-17 US claimed
EP-3290461-A1 POLYIMIDE RESIN AND FILM USING SAME Kolon Industries, Inc. (KR) 2018-03-07 EP claimed
EP-2555053-B1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2017-10-18 EP claimed
US-9758623-B2 Polyimide precursor and polyimide UBE INDUSTRIES, LTD. (JP) 2017-09-12 US claimed
US-9580555-B2 Transparent polyamide-imide resin and film using same KOLON INDUSTRIES, INC. (KR) 2017-02-28 US claimed
US-20160319076-A1 TRANSPARENT POLYAMIDE-IMIDE RESIN AND FILM USING SAME KOLON INDUSTRIES, INC. (KR) 2016-11-03 US claimed
EP-3088440-A1 TRANSPARENT POLYAMIDE-IMIDE RESIN AND FILM USING SAME Kolon Industries, Inc. (KR) 2016-11-02 EP claimed
US-20160032056-A1 POLYIMIDE PRECURSOR AND POLYIMIDE UBE CORPORATION (JP) 2016-02-04 US claimed
WO-2024247983-A1 COMPOSITION 東レ株式会社 2024-12-05 WO disclosed
CN-117567742-B Preparation method of yellowing-resistant transparent polyimide substrate material 株洲时代新材料科技股份有限公司 2024-03-29 CN disclosed
CN-117567742-A Preparation method of yellowing-resistant transparent polyimide substrate material 株洲时代新材料科技股份有限公司 2024-02-20 CN disclosed
US-6524764-B1 Alkali-developable; polyamide, phenol compound and/or ester of a naphthoquinone diazide sulphonic acid TORAY INDUSTRIES, INC. (JP) 2003-02-25 US disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed
EP-1132773-A1 POSITIVE-TYPE PHOTOSENSITIVE POLYIMIDE PRECURSOR COMPOSITION TORAY INDUSTRIES, INC. (JP) 2001-09-12 EP disclosed
EP-1037112-A1 POSITIVE PHOTOSENSITIVE RESIN PRECURSOR COMPOSITION AND PROCESS FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2000-09-20 EP disclosed