SCHEMBL103733

SCHEMBL103733

Nc1cccc(C(F)(F)F)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.42
CA2 P00918 2/20 0.39
POLB P06746 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 4/20 0.37
ALOX15 P16050 1/20 0.37
PTGS1 P23219 1/20 0.36
GAA P10253 2/20 0.35
GLA P06280 1/20 0.35
MAPK1 P28482 1/20 0.35
IDO1 P14902 2/20 0.35
MPL P40238 1/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
CUL4A Q13619 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756206 0.86 MMP2 (0.42) MMP2CA2POLBALDH1A1TDP1
SCHEMBL396017 0.83 CA2 (0.55) MMP2CA2POLBALDH1A1TDP1
SCHEMBL30390082 0.83 MMP2 (0.39) MMP2CA2POLBALDH1A1TDP1
SCHEMBL6757407 0.83 MMP2 (0.39) MMP2CA2POLBALDH1A1TDP1
SCHEMBL689226 0.79 MMP2 (0.37) MMP2CA2ALDH1A1TDP1TSHR
SCHEMBL19837804 0.78 MMP2 (0.36) MMP2CA2POLBTDP1L3MBTL1
SCHEMBL19326634 0.78 MMP2 (0.36) MMP2CA2TSHRALOX15
SCHEMBL564371 0.77 CA2 (0.50) MMP2CA2ALDH1A1TDP1TSHR
SCHEMBL6282684 0.77 CA2 (0.70) MMP2CA2POLBALDH1A1TDP1
SCHEMBL16738114 0.77 MMP2 (0.35) MMP2CA2TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10253006-B2 Assay for the detection of the phenylpiperazine family RANDOX LABORATORIES LIMITED (GB) 2019-04-09 US claimed
US-20160229824-A1 ASSAY FOR THE DETECTION OF THE PHENYLPIPERAZINE FAMILY NORTHERN BANK LIMITED (IE) 2016-08-11 US claimed
EP-4619388-A1 CATHEPSIN L INHIBITORS Biofront Therapeutics (Beijing) Co., Ltd. (CN) 2025-09-24 EP disclosed
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. 2025-05-22 US disclosed
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-119212781-A Method for preparing m-hydroxy benzotrifluoride (MHBTF) 迪帕克亚硝酸盐有限公司 2024-12-27 CN disclosed
CN-119212781-A Method for preparing m-hydroxy benzotrifluoride (MHBTF) 迪帕克亚硝酸盐有限公司 2024-12-27 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20240409533-A1 HMOX1 INDUCERS Astellas Engineered Small Molecules US, Incorporated 2024-12-12 US disclosed
CN-113874074-B HMOX1 inducers 米托布里奇公司 2024-11-01 CN disclosed
US-12071433-B2 HMOX1 inducers Astellas Engineered Small Molecules US, Incorporated (US) 2024-08-27 US disclosed
US-5886044-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-03-23 US disclosed
EP-0896531-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1999-02-17 EP disclosed
US-5780483-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1998-07-14 US disclosed
WO-1997049286-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-12-31 WO disclosed
EP-0809492-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-12-03 EP disclosed
WO-1997029743-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-08-21 WO disclosed
WO-1996025157-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-22 WO disclosed
US-4263441-A BENZOXAZOLE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
EP-0002030-A1 Fluorinated benzazole derivatives, method for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC MMP2 4502/4885CA2 4707/4885POLB 238/4885
US-20240409533-A1 HMOX1 INDUCERS HMOX1, HMOX2, HMBS MMP2 1059/4885CA2 2497/4885POLB 3184/4885
US-12071433-B2 HMOX1 inducers HMOX1, HMOX2, HMBS MMP2 994/4885CA2 2228/4885POLB 2840/4885
US-10253006-B2 Assay for the detection of the phenylpiperazine family METAP2, DCPS, NPEPPS MMP2 1087/4885CA2 3647/4885POLB 2782/4885
US-20160229824-A1 ASSAY FOR THE DETECTION OF THE PHENYLPIPERAZINE FAMILY METAP2, DCPS, NPEPPS MMP2 1087/4885CA2 3647/4885POLB 2782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.