Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350317 | 1.00 | LMNA (0.61) | LMNADNM1BCHEMEN1KMT2A | |
| SCHEMBL3349419 | 0.90 | BCHE (0.49) | LMNADNM1BCHEF2BACE1 | |
| SCHEMBL3348880 | 0.87 | LMNA (0.50) | LMNADNM1MEN1KMT2ACHRM2 | |
| SCHEMBL3351268 | 0.87 | ALDH1A1 (0.47) | LMNAMEN1KMT2APNMTF2 | |
| SCHEMBL6894816 | 0.86 | BCHE (0.53) | LMNADNM1BCHEBACE1 | |
| SCHEMBL3351836 | 0.86 | BCHE (0.53) | LMNADNM1BCHEBACE1 | |
| Hydrochloric Acid SCHEMBL5218955 | 0.86 | LMNA (0.48) | LMNAMEN1KMT2A | |
| SCHEMBL3353939 | 0.85 | BCHE (0.61) | LMNADNM1BCHEMEN1KMT2A | |
| SCHEMBL2605624 | 0.85 | BCHE (0.61) | LMNADNM1BCHEMEN1KMT2A | |
| SCHEMBL496172 | 0.85 | BCHE (0.61) | LMNADNM1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |