Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894291 | 0.90 | GRIN2D (0.34) | BCHE | |
| SCHEMBL3407567 | 0.87 | HIF1A (0.34) | BCHE | |
| SCHEMBL6894362 | 0.85 | — | — | |
| SCHEMBL4608372 | 0.81 | HTR2A (0.34) | — | |
| SCHEMBL258245 | 0.79 | KDM4E (0.33) | KDM4EALDH1A1GAA | |
| SCHEMBL258351 | 0.76 | TLR8 (0.36) | LMNAGAAKMT2ATDP1BCHE | |
| SCHEMBL11424021 | 0.76 | TDP1 (0.37) | TDP1 | |
| SCHEMBL6038388 | 0.76 | TAAR1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL4841054 | 0.76 | TDP1 (0.37) | TDP1 | |
| SCHEMBL295333 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888262-B1 | CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES | BASF AG (DE) | 2004-06-02 | — | — | EP | disclosed |
| US-6521780-B1 | Cycloalkylmalonic ester derivatives as potential active substances in the drugs and crop protection; combinatorial chemistry | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-18 | — | — | US | disclosed |
| US-6469056-B1 | VERY SELECTIVE INHIBITORS OF ENDOTHELIN CONVERTING ENZYME WITH ACTIVITIES IN THE PICOMOLAR RANGE FOR USE AS HYPOTENSIVE AGENTS | ABBOTT LABORATORIES | 2002-10-22 | — | — | US | disclosed |
| EP-0906324-B1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AG (DE) | 2001-08-01 | — | — | EP | disclosed |
| US-6242583-B1 | COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| EP-1023282-A1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS, THEIR PREPARATION AND USE AS ECE-INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-02 | — | — | EP | disclosed |
| EP-1023318-A1 | DIPEPTIDES FOR THE TREATMENT OF DISEASES RELATED TO THE BIOLOGICAL EFFECT OF ENDOTHELIN | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019320-A1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS, THEIR PREPARATION AND USE AS ECE-INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999019346-A1 | DIPEPTIDES FOR THE TREATMENT OF DISEASES RELATED TO THE BIOLOGICAL EFFECT OF ENDOTHELIN | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |
| EP-0906324-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0888262-A1 | CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997045436-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | disclosed |
| WO-1997034852-A1 | CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-25 | — | — | WO | disclosed |