Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258351 | 0.89 | TLR8 (0.36) | GAAATMCYP1A2CYP2A6 | |
| SCHEMBL360721 | 0.87 | KCNH2 (0.39) | KDM4EALDH1A1GAA | |
| SCHEMBL3281783 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL3671647 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL409777 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL3670490 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL2460770 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL3670506 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL9145259 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL3282347 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704913-A | A kind of spiro fluorene compound and its application | 瑞声科技（南京）有限公司 | 2019-05-03 | — | — | CN | claimed |
| US-8334391-B2 | Functionalized heteroacenes | XEROX CORPORATION (US) | 2012-12-18 | — | — | US | claimed |
| US-20090306442-A1 | OLIGOMERISATION CATALYST WITH PENDANT DONOR GROUPS | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2009-12-10 | — | — | US | claimed |
| EP-2024305-A2 | OLIGOMERISATION CATALYST WITH PENDANT DONOR GROUPS | Sasol Technology (Pty) Ltd (ZA) | 2009-02-18 | — | — | EP | claimed |
| US-7372071-B2 | Functionalized heteroacenes and electronic devices generated therefrom | XEROX CORPORATION (US) | 2008-05-13 | — | — | US | claimed |
| WO-2007138545-A2 | OLIGOMERISATION CATALYST WITH PENDANT DONOR GROUPS | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2007-12-06 | — | — | WO | claimed |
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135350-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | claimed |
| US-20070260069-A1 | Functionalized heteroacenes | XEROX CORPORATION | 2007-11-08 | — | — | US | claimed |
| US-20070235721-A1 | Functionalized heteroacenes and electronic devices generated therefrom | XEROX CORPORATION | 2007-10-11 | — | — | US | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| US-5512188-A | DURABLE LUBRICANTS HAVING REDUCED FLAKING | NIPPON OIL CO., LTD. (JP) | 1996-04-30 | — | — | US | claimed |
| US-5462683-A | Thickener, boron nitride powder, extreme pressure agent comprising molybdenum compound, and sulfur and phosphorus containing compounds; nonflaking | NIPPON OIL CO., LTD. (JP) | 1995-10-31 | — | — | US | claimed |
| US-RE31300-E | Process for preparing alkyl- or arylphosphonothioic dihalides | STAUFFER CHEMICAL COMPANY (US) | 1983-07-05 | — | — | US | claimed |
| US-4130583-A | AUTOGENOUS PRESSURE | STAUFFER CHEMICAL COMPANY (US) | 1978-12-19 | — | — | US | claimed |
| US-4052463-A | PROCESS FOR PREPARING TERTIARY PHOSPHINE SULFIDES AND OXIDES | STAUFFER CHEMICAL COMPANY (US) | 1977-10-04 | — | — | US | claimed |
| US-4000190-A | FROM DIALKYL OR DIARYL DISULFIDES, PHOSPHORUS, AND PHOSPHORUS TRIHALIDE | STAUFFER CHEMICAL COMPANY (US) | 1976-12-28 | — | — | US | claimed |
| US-3968156-A | Process for preparing alkyl-or arylphosphonothioic dihalides | STAUFFER CHEMICAL COMPANY (US) | 1976-07-06 | — | — | US | claimed |
| US-3962323-A | PHOSPHORUS TRIHALIDE | STAUFFER CHEMICAL COMPANY (US) | 1976-06-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260069-A1 | Functionalized heteroacenes | SOD1, AHR, NR0B2 | KDM4E 3546/4885ALDH1A1 2135/4885GAA 4806/4885 |
| US-20090306442-A1 | OLIGOMERISATION CATALYST WITH PENDANT DONOR GROUPS | NOD1, ORC3, APEX1 | KDM4E 4712/4885ALDH1A1 3141/4885GAA 3714/4885 |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | KDM4E 2424/4885ALDH1A1 846/4885GAA 3532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.