Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729430 | 0.93 | ABCC2 (0.33) | ABCC2 | |
| SCHEMBL6886895 | 0.91 | ESR1 (0.33) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL6887295 | 0.90 | ESR1 (0.34) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7634446 | 0.87 | CACNA1C (0.34) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL6892382 | 0.84 | ESR1 (0.33) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL6891413 | 0.84 | ESR1 (0.33) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL7727951 | 0.84 | ABCC2 (0.33) | ABCC2 | |
| SCHEMBL6891569 | 0.84 | CACNA1C (0.34) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL6773445 | 0.84 | CACNA1C (0.34) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL6887322 | 0.83 | CACNA1C (0.35) | ESR1PTGS1PDE4ACACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030149016-A1 | Novel carbapenem derivatives | KANO YUKO (JP) | 2003-08-07 | — | — | US | disclosed |
| EP-1101766-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149016-A1 | Novel carbapenem derivatives | DPEP1, TMPRSS15, STK35 | ESR1 4489/4885PTGS1 1759/4885PDE4A 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.