Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545665 | 0.79 | CA2 (0.45) | CA2CA1NNMTCA12CA9 | |
| Potassium Ion SCHEMBL30884945 | 0.76 | CA2 (0.42) | CA2CA1NNMTCA12CA9 | |
| SCHEMBL3646701 | 0.72 | KMT2A (0.48) | CA2CA1CA12CA9CA14 | |
| Bromide SCHEMBL7178411 | 0.69 | PARP10 (0.41) | CA2CA1NNMTACHEPARP10 | |
| SCHEMBL2833136 | 0.68 | KDM4E (0.43) | NNMTTSHRALDH1A1KMT2APARP1 | |
| SCHEMBL30488814 | 0.68 | KDM4E (0.43) | NNMTTSHRALDH1A1KMT2APARP1 | |
| Terephthalamide SCHEMBL23774 | 0.68 | PARP1 (0.71) | CA2CA1NNMTCA12CA9 | |
| SCHEMBL1615851 | 0.67 | CA1 (0.47) | CA2CA1CA12CA9CA14 | |
| SCHEMBL29618255 | 0.67 | MEN1 (0.68) | NNMTTSHRKMT2APARP1POLB | |
| SCHEMBL128526 | 0.67 | MEN1 (0.68) | NNMTTSHRKMT2APARP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |