Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270418 | 0.89 | CHRM1 (0.78) | CHRM1 | |
| SCHEMBL6890001 | 0.82 | SMN1; SMN2 (0.51) | KDM4ERAB9A | |
| SCHEMBL6892258 | 0.82 | GAA (0.56) | KDM4ERAB9A | |
| SCHEMBL18756582 | 0.81 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL6888967 | 0.81 | MAPT (0.57) | RAB9A | |
| SCHEMBL6891034 | 0.81 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL18725352 | 0.80 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL6892642 | 0.80 | TSHR (0.49) | CHRM1RAB9A | |
| SCHEMBL17656777 | 0.79 | CHRM1 (0.51) | CHRM1KDM4ERAB9A | |
| SCHEMBL6893778 | 0.79 | CHRM1 (0.51) | CHRM1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084368-A1 | QUINOLINE AMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |