Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6891690 | 0.95 | EDNRB (0.31) | EDNRBEDNRACACNA1B | |
| Hydrochloric Acid SCHEMBL6895108 | 0.91 | NISCH (0.30) | — | |
| Hydrochloric Acid SCHEMBL6889795 | 0.86 | ADRA2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL6892861 | 0.86 | BRD4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6884572 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL6886359 | 0.86 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6886306 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL6891500 | 0.84 | EDNRB (0.33) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL6892204 | 0.84 | EDNRB (0.33) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL6886385 | 0.84 | CACNA1B (0.32) | EDNRBEDNRACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004315496-A | FUSED HETEROCYCLIC RING COMPOUND | TAKEDA CHEM IND LTD | 2004-11-11 | — | — | JP | disclosed |