SCHEMBL6893809

SCHEMBL6893809

N#Cc1ccc(CN2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4o3)CC2=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 16/20 0.44
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
GPR35 Q9HC97 1/20 0.41
CNR1 P21554 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.38
TRPV4 Q9HBA0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6893828 0.83 F10 (0.63) F10
SCHEMBL6895154 0.82 F10 (0.49) F10FNTAFNTBCNR1TRPM8
SCHEMBL7051365 0.77 F10 (0.46) F10FNTAFNTBCNR1
SCHEMBL7058209 0.77 KMT2A (0.47) F10CNR1TRPM8TRPV4
Hydrochloric Acid SCHEMBL6894725 0.77 DRD2 (0.45) F10
SCHEMBL6891892 0.75 F10 (0.41) F10FNTAFNTBCNR1TRPM8
SCHEMBL6895642 0.74 F10 (0.50) F10
SCHEMBL6895006 0.73 PKM (0.48)
SCHEMBL6894382 0.73 USP2 (0.47) F10FNTAFNTBCNR1
SCHEMBL6894345 0.73 CYP3A4 (0.42) F10FNTAFNTBCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680312-B2 FOR THERAPY OF CARDIAC INFARCTION, CEREBRAL THROMBOSIS; INHIBIT ACTIVATED COAGULATION FACTOR X (FXA) TO SHOW ANTI-COAGULANT ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-01-20 US disclosed
US-20020193382-A1 Sulfonamide derivatives, their production and use TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) 2002-12-19 US disclosed
US-6403595-B1 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-11 US disclosed
EP-1054005-A1 SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193382-A1 Sulfonamide derivatives, their production and use F12, F11, F2 F10 5/4885FNTA 2027/4885FNTB 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.