Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15514529 | 1.00 | PLG (0.50) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL30337771 | 1.00 | PLG (0.50) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL7448393 | 0.91 | CYP2D6 (0.43) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL11693682 | 0.88 | SLC6A12 (0.50) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL10341442 | 0.86 | PLG (0.60) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL19650816 | 0.86 | SLC6A12 (0.46) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL14416203 | 0.86 | PLG (0.60) | PLGPLATLMNAANPEPENPEP | |
| Hydrochloric Acid SCHEMBL9991894 | 0.84 | PLG (0.58) | PLGPLATLMNAANPEPENPEP | |
| Hydrochloric Acid SCHEMBL1934473 | 0.84 | PLG (0.58) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL1421999 | 0.78 | LMNA (0.47) | PLGPLATLMNASLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480639-A1 | COMBINATIONS OF AN ALPHA-2-DELTA LIGAND WITH A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 | Warner-Lambert Company LLC (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003070237-A1 | COMBINATIONS OF AN ALPHA-2-DELTA LIGAND WITH A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 | WARNER-LAMBERT COMPANY LLC (US) | 2003-08-28 | — | — | WO | disclosed |