Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449526 | 0.96 | MAPT (0.49) | MAPTMCHR1NPBWR1SLC6A3 | |
| SCHEMBL3885054 | 0.85 | MAPT (0.61) | MAPTALDH1A1MAPK1MCHR1NPBWR1 | |
| SCHEMBL19436600 | 0.81 | MAPT (0.50) | MAPTALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL3554528 | 0.80 | MAPT (0.48) | MAPTALDH1A1MAPK1MCHR1NPBWR1 | |
| SCHEMBL7913532 | 0.80 | SMN1; SMN2 (0.46) | MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10488320 | 0.80 | CTSS (0.40) | — | |
| SCHEMBL3552397 | 0.79 | MAPT (0.56) | MAPTALDH1A1MAPK1MCHR1NPBWR1 | |
| SCHEMBL3552399 | 0.79 | MAPT (0.56) | MAPTALDH1A1MAPK1MCHR1NPBWR1 | |
| SCHEMBL9660476 | 0.79 | MAPT (0.56) | MAPTALDH1A1MAPK1MCHR1NPBWR1 | |
| SCHEMBL28149835 | 0.79 | MAPT (0.44) | MAPTALDH1A1MAPK1MCHR1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835277-A | Acrylic pyrrolidine or piperidine | HOECHST CELANESE CORPORATION (US) | 1989-05-30 | — | — | US | claimed |
| EP-1093454-B1 | CHIRAL COMPOUNDS AND THEIR USE AS DOPING AGENTS IN LIQUID CRYSTALS | ROLIC AG (CH) | 2004-09-22 | — | — | EP | disclosed |
| US-6569356-B1 | Chiral compounds and their use as doping agents in liquid crystals | ROLIC AG (CH) | 2003-05-27 | — | — | US | disclosed |
| US-4835277-A | Acrylic pyrrolidine or piperidine | HOECHST CELANESE CORPORATION (US) | 1989-05-30 | — | — | US | disclosed |
| US-4804255-A | Acrylic polymers exhibiting chiral and nonlinear optical properties | HOECHST CELANESE CORP. (US) | 1989-02-14 | — | — | US | disclosed |
| US-4755574-A | Acrylic polymers exhibiting chiral and nonlinear optical properties | HOECHST CELANESE CORPORATION (US) | 1988-07-05 | — | — | US | disclosed |