SCHEMBL9449526

SCHEMBL9449526

C=C(C(=O)OC)C1CCCCN1c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
MCHR1 Q99705 8/20 0.45
NPBWR1 P48145 7/20 0.45
SLC6A3 Q01959 1/20 0.42
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6893874 0.96 MAPT (0.50) MAPTMCHR1NPBWR1SLC6A3
SCHEMBL3885054 0.82 MAPT (0.61) MAPTMCHR1NPBWR1SLC6A3
SCHEMBL19436600 0.77 MAPT (0.50) MAPT
SCHEMBL7913532 0.77 SMN1; SMN2 (0.46) MAPTKMT2A
SCHEMBL3554528 0.77 MAPT (0.48) MAPTMCHR1NPBWR1KMT2A
SCHEMBL10488320 0.76 CTSS (0.40)
SCHEMBL3130442 0.76 MCHR1 (0.47) MAPTMCHR1NPBWR1KMT2A
SCHEMBL3130434 0.76 MCHR1 (0.47) MAPTMCHR1NPBWR1KMT2A
SCHEMBL3552397 0.76 MAPT (0.56) MAPTMCHR1NPBWR1KMT2A
SCHEMBL3552399 0.76 MAPT (0.56) MAPTMCHR1NPBWR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0532517-A4 OPTICAL PARAMETRIC AMPLIFIER 1993-08-18 EP disclosed
EP-0532517-A1 OPTICAL PARAMETRIC AMPLIFIER HOECHST CELANESE CORPORATION (US) 1993-03-24 EP disclosed
WO-1992019995-A1 NONLINEAR OPTICALLY RESPONSIVE POLYMERIC WAVEGUIDES HOECHST CELANESE CORPORATION (US) 1992-11-12 WO disclosed
US-5143577-A SMOOTH-WALL POLYMERIC CHANNEL AND RIB WAVEGUIDES EXHIBITING LOW OPTICAL LOSS HOECHST CELANESE CORPORATION (US) 1992-09-01 US disclosed
WO-1992013726-A1 SMOOTH-WALL POLYMERIC CHANNEL AND RIB WAVEGUIDES EXHIBITING LOW OPTICAL LOSS HOECHST CELANESE CORPORATION (US) 1992-08-20 WO disclosed
US-5131068-A THICKNESS VARIATION INSENSITIVE FREQUENCY DOUBLING POLYMERIC WAVEGUIDE HOECHST CELANESE CORP. (US) 1992-07-14 US disclosed
US-5106211-A Formation of polymer channel waveguides by excimer laser ablation and method of making same HOECHST CELANESE CORP. (US) 1992-04-21 US disclosed
WO-1992003752-A1 PRODUCTION OF NONLINEAR OPTICALLY RESPONSIVE POLYMERIC WAVEGUIDES HOECHST CELANESE CORPORATION (US) 1992-03-05 WO disclosed
WO-1992002856-A1 PRODUCTION OF POLYMERIC OPTICAL WAVEGUIDES HOECHST CELANESE CORPORATION (US) 1992-02-20 WO disclosed
WO-1991019220-A1 OPTICAL PARAMETRIC AMPLIFIER HOECHST CELANESE CORPORATION (US) 1991-12-12 WO disclosed
US-5064265-A Optical parametric amplifier HOECHST CELANESE CORP. (US) 1991-11-12 US disclosed
US-5061028-A Polymeric waveguides with bidirectional poling for radiation phase-matching HOECHST CELANESE CORPORATION (US) 1991-10-29 US disclosed
US-5039186-A Production of nonlinear optically responsive polymeric waveguides HOECHST CELANESE CORP. (US) 1991-08-13 US disclosed
EP-0402803-A2 Polarization-insensitive interferometric waveguide electrooptic modulator HOECHST CELANESE CORPORATION (US) 1990-12-19 EP disclosed
EP-0402804-A2 Polarization-insensitive interferometric waveguide electrooptic modulator HOECHST CELANESE CORPORATION (US) 1990-12-19 EP disclosed
US-4971416-A Polymeric waveguide device for phase matched second harmonic generation HOECHST CELANESE CORP. (US) 1990-11-20 US disclosed
US-4936644-A Polarization-insensitive interferometric waveguide electrooptic modulator HOECHST CELANESE CORP. (US) 1990-06-26 US disclosed
US-4932738-A Polarization-insensitive interferometric waveguide electrooptic modulator HOECHST CELANESE CORP. (US) 1990-06-12 US disclosed
EP-0368042-A2 Frequency doubling polymeric waveguide HOECHST CELANESE CORPORATION (US) 1990-05-16 EP disclosed
US-4865406-A SUPPORTED POLYMERIC THIN FILM EXHIBITING SECOND ORDER NONLINEA R OPTICAL RESPONSE HOECHST CELANESE CORP. (US) 1989-09-12 US disclosed