Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084718 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL6893874 | 0.80 | MAPT (0.50) | SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL7978483 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL7981185 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL9449526 | 0.77 | MAPT (0.49) | MAPTKMT2A | |
| SCHEMBL9703576 | 0.76 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL15522549 | 0.74 | KMT2A (0.55) | SMN1; SMN2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL8404563 | 0.74 | MAPT (0.42) | SMN1; SMN2ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL10120229 | 0.72 | ITGB2 (0.48) | SMN1; SMN2ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL28493144 | 0.72 | AR (0.55) | SMN1; SMN2MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093454-A1 | CHIRAL COMPOUNDS AND THEIR USE AS DOPING AGENTS IN LIQUID CRYSTALS | Rolic AG (CH) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000002856-A1 | CHIRAL COMPOUNDS AND THEIR USE AS DOPING AGENTS IN LIQUID CRYSTALS | ROLIC AG (CH) | 2000-01-20 | — | — | WO | disclosed |
| US-4804255-A | Acrylic polymers exhibiting chiral and nonlinear optical properties | HOECHST CELANESE CORP. (US) | 1989-02-14 | — | — | US | disclosed |