Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898893 | 0.85 | CASP6 (0.53) | CASP6TSHRLMNAMEN1KMT2A | |
| SCHEMBL5098503 | 0.76 | CASP6 (0.62) | CASP6TSHRLMNAMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL30234086 | 0.75 | VCAM1 (0.77) | CASP6TSHRLMNAMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL6101 | 0.75 | VCAM1 (0.77) | CASP6TSHRLMNAMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608939 | 0.74 | VCAM1 (0.74) | CASP6TSHRLMNAMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608947 | 0.74 | VCAM1 (0.74) | CASP6TSHRLMNAMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL8028245 | 0.74 | VCAM1 (0.74) | CASP6TSHRLMNAMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL28165768 | 0.74 | VCAM1 (0.74) | CASP6TSHRLMNAMEN1KMT2A | |
| SCHEMBL2681764 | 0.73 | USP7 (0.60) | TSHRMAPK1POLB | |
| SCHEMBL3164872 | 0.72 | TP53 (0.48) | TSHRLMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |