Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275146 | 0.89 | POLB (0.64) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL9695987 | 0.75 | CYP1A2 (0.58) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL23718184 | 0.74 | TSHR (0.84) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL1520616 | 0.73 | POLB (1.00) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL7568029 | 0.71 | ALDH1A1 (0.49) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL16213836 | 0.70 | TSHR (0.65) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL4590439 | 0.70 | POLB (0.59) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL2942696 | 0.70 | POLB (0.59) | POLBTSHRALDH1A1HTTCYP2C19 | |
| Naphthalene SCHEMBL27729148 | 0.70 | LMNA (0.40) | POLBTSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL16332691 | 0.70 | ATM (0.49) | POLBTSHRALDH1A1HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428284-A2 | HYDROPHILIC POLYMERS AND THEIR USE IN ELECTROCHEMICAL CELLS | ITM Power Ltd. (GB) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003023890-A2 | HYDROPHILIC POLYMERS AND THEIR USE IN ELECTROCHEMICAL CELLS | ITM POWER LTD. (GB) | 2003-03-20 | — | — | WO | disclosed |