Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495694 | 0.80 | HDAC4 (0.43) | ALDH1A1FFAR1FFAR4HDAC4HDAC2 | |
| SCHEMBL430965 | 0.76 | ABL1 (0.46) | FFAR1FFAR4HDAC4HDAC2HDAC8 | |
| SCHEMBL2489138 | 0.74 | MAOB (0.40) | FFAR1FFAR4HDAC4HDAC2HDAC8 | |
| SCHEMBL6884179 | 0.70 | SLC6A11 (0.43) | MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3024594 | 0.70 | FFAR1 (0.42) | MAPTALDH1A1HTTFFAR1FFAR4 | |
| SCHEMBL2489493 | 0.69 | HDAC4 (0.50) | HTTFFAR1FFAR4HDAC4HDAC2 | |
| SCHEMBL9959026 | 0.68 | ABL1 (0.46) | FFAR1FFAR4HDAC4HDAC2HDAC8 | |
| SCHEMBL2494971 | 0.68 | MEN1 (0.50) | ALDH1A1HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL6409694 | 0.67 | FFAR4 (0.54) | FFAR1FFAR4 | |
| SCHEMBL5385988 | 0.67 | BCL9 (0.46) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040241713-A1 | Composition for immobilization of biological macromolecules in hydrogels, a method for preparing a composition, a biochip, and a method for performing the PCR over biochip | INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A. ENGELGARDTA ROSSIISKOI AKADEMII NAUK | 2004-12-02 | — | — | US | disclosed |