⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770348 | 0.73 | — | — | |
| SCHEMBL6778217 | 0.68 | — | — | |
| SCHEMBL3460400 | 0.49 | ALOX15 (0.53) | — | |
| SCHEMBL2054431 | 0.47 | MAPT (0.50) | — | |
| SCHEMBL3459457 | 0.47 | IDO1 (0.58) | — | |
| SCHEMBL1398606 | 0.46 | — | — | |
| SCHEMBL5158961 | 0.42 | — | — | |
| SCHEMBL8453182 | 0.40 | — | — | |
| SCHEMBL1741746 | 0.38 | — | — | |
| SCHEMBL1413229 | 0.35 | GPR35 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |