SCHEMBL6895490

SCHEMBL6895490

CCC(CC)Cc1[c]cccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20269672 0.89
SCHEMBL340706 0.86 ALDH1A1 (0.41) LMNA
SCHEMBL1071095 0.82 TRPA1 (0.32) TRPA1LMNA
SCHEMBL25309170 0.82 TRPA1 (0.32) TRPA1LMNA
SCHEMBL2696383 0.80
SCHEMBL10488035 0.80
SCHEMBL136235 0.78 GABRA1 (0.35)
SCHEMBL3669261 0.78 PRSS1 (0.39) LMNA
SCHEMBL3677339 0.78 PRSS1 (0.39) LMNA
SCHEMBL3671160 0.78 PRSS1 (0.39) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104370801-B Carbazole compound and application thereof 东曹株式会社 2017-11-03 CN disclosed
CN-104326968-B Carbazole compound and use thereof 东曹株式会社 2017-04-12 CN disclosed
EP-0888262-B1 CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES BASF AG (DE) 2004-06-02 EP disclosed
US-6521780-B1 Cycloalkylmalonic ester derivatives as potential active substances in the drugs and crop protection; combinatorial chemistry BASF AKTIENGESELLSCHAFT (DE) 2003-02-18 US disclosed
EP-0906324-B1 CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS BASF AG (DE) 2001-08-01 EP disclosed
US-6242583-B1 COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed
EP-0888262-A1 CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-01-07 EP disclosed
WO-1997034852-A1 CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1997-09-25 WO disclosed