SCHEMBL6895682

SCHEMBL6895682

CC(C=Cc1ccccc1)=Cc1ccc(C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.60
RAB9A P51151 2/20 0.60
NPC1 O15118 1/20 0.60
POLB P06746 1/20 0.60
ALDH1A1 P00352 3/20 0.56
CYP1B1 Q16678 1/20 0.56
CYP3A4 P08684 1/20 0.56
HPGD P15428 1/20 0.56
TRPM8 Q7Z2W7 2/20 0.56
TSHR P16473 1/20 0.52
GLA P06280 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
EGFR P00533 1/20 0.51
MMP1 P03956 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
FOS P01100 1/20 0.49
JUN P05412 1/20 0.49
ALOX15 P16050 1/20 0.48
NFE2L2 Q16236 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23458038 1.00 MAPT (0.60) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL5438537 1.00 MAPT (0.60) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL23457954 1.00 MAPT (0.60) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL29919779 0.92 MAPT (0.53) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL23458161 0.92 MAPT (0.53) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL23457945 0.90 ALDH1A1 (0.61) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL3084338 0.90 ALDH1A1 (0.61) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL29382 0.90 ALDH1A1 (0.61) MAPTRAB9ANPC1POLBALDH1A1
SCHEMBL499104 0.85 CYP3A4 (0.53) MAPTRAB9AALDH1A1CYP1B1CYP3A4
SCHEMBL15048548 0.85 FOS (0.58) MAPTRAB9ANPC1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3055356-A1 FLAME RETARDANT THERMOPLASTIC COMPOSITIONS WITH IMPROVED PROPERTIES SABIC Global Technologies B.V. (NL) 2016-08-17 EP disclosed
WO-2015054179-A1 FLAME RETARDANT THERMOPLASTIC COMPOSITIONS WITH IMPROVED PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-04-16 WO disclosed
EP-1481026-A2 WEATHERABLE STYRENIC BLENDS WITH IMPROVED TRANSLUCENCY GENERAL ELECTRIC COMPANY (US) 2004-12-01 EP disclosed
WO-2003074608-A2 WEATHERABLE STYRENIC BLENDS WITH IMPROVED TRANSLUCENCY GENERAL ELECTRIC COMPANY (US) 2003-09-12 WO disclosed