Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047161 | 0.90 | POLB (0.39) | POLBLMNAPKMNPC1RAB9A | |
| SCHEMBL6895269 | 0.85 | KDM4E (0.46) | POLBLMNAPKMRNASE1HCAR2 | |
| SCHEMBL6896046 | 0.85 | SLC29A1 (0.41) | — | |
| SCHEMBL6046977 | 0.83 | POLB (0.50) | POLBLMNAABL1RIN1MAPT | |
| SCHEMBL6890238 | 0.82 | POLB (0.39) | POLBABL1RIN1MAPTNPC1 | |
| SCHEMBL6890005 | 0.76 | POLB (0.50) | POLBLMNAABL1RIN1MAPT | |
| SCHEMBL6046959 | 0.75 | POLB (0.42) | POLBLMNAABL1RIN1MAPT | |
| SCHEMBL6046965 | 0.73 | NT5E (0.40) | POLBLMNAPKMMAPTALDH1A1 | |
| SCHEMBL6573680 | 0.72 | RNASE1 (0.59) | PKMRNASE1 | |
| SCHEMBL6572381 | 0.72 | RNASE1 (0.59) | PKMRNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212338-B1 | Nucleoside derivatives with photolabile protective groups | DEUTSCHES KREBSFORSCH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-6756492-B1 | Nucleoside derivatives with photo-unstable protective groups | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) | 2004-06-29 | — | — | US | disclosed |