Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891890 | 0.90 | POLB (0.48) | POLBLMNANPC1RAB9APKM | |
| SCHEMBL6046959 | 0.87 | POLB (0.42) | POLBTYMPLMNANPC1RAB9A | |
| SCHEMBL6046979 | 0.81 | TYMP (0.45) | POLBTYMPLMNANPC1RAB9A | |
| SCHEMBL6890238 | 0.80 | POLB (0.39) | POLBNPC1RAB9A | |
| SCHEMBL6895269 | 0.76 | KDM4E (0.46) | POLBTYMPLMNAPKMALDH1A1 | |
| SCHEMBL6896046 | 0.76 | SLC29A1 (0.41) | — | |
| SCHEMBL8712130 | 0.75 | POLB (0.42) | POLBTYMPLMNANPC1RAB9A | |
| SCHEMBL6890940 | 0.75 | TYMP (0.41) | TYMPNPC1RAB9AALDH1A1 | |
| SCHEMBL6046977 | 0.74 | POLB (0.50) | POLBLMNAALDH1A1 | |
| SCHEMBL6703966 | 0.74 | POLB (0.56) | POLBTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212338-B1 | Nucleoside derivatives with photolabile protective groups | DEUTSCHES KREBSFORSCH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-6756492-B1 | Nucleoside derivatives with photo-unstable protective groups | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) | 2004-06-29 | — | — | US | disclosed |