Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386818 | 0.89 | — | — | |
| SCHEMBL6590774 | 0.84 | CTSL (0.35) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6593138 | 0.82 | CTSL (0.31) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4212772 | 0.81 | CTSS (0.35) | MAPK1CTSLALDH1A1LMNACTSB | |
| SCHEMBL5971691 | 0.81 | MAPK1 (0.36) | MAPK1CTSLALDH1A1LMNACTSB | |
| SCHEMBL6589031 | 0.81 | — | — | |
| SCHEMBL3955650 | 0.79 | CTSL (0.36) | MAPK1CTSLCTSBCTSSCTSK | |
| SCHEMBL3955653 | 0.79 | CTSL (0.36) | MAPK1CTSLCTSBCTSSCTSK | |
| SCHEMBL6589335 | 0.76 | — | — | |
| SCHEMBL4762162 | 0.73 | MAPK1 (0.41) | MAPK1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231922-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1229914-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1233771-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1229912-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1229911-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1233771-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1231922-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1229911-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-1229912-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-1229914-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034159-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034153-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034155-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034154-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034156-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |