Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28862293 | 0.92 | PPARG (0.50) | EPHX1SOAT1GFERPPARGPPARD | |
| SCHEMBL3444924 | 0.86 | EPHX1 (0.48) | EPHX1TSHRPPARGPPARDPPARA | |
| SCHEMBL14269025 | 0.84 | LDHA (0.57) | SOAT1GFERALDH1A1CYP3A4TSHR | |
| SCHEMBL15658145 | 0.84 | PPARG (0.54) | EPHX1SOAT1PPARGPPARDPPARA | |
| SCHEMBL15661707 | 0.81 | EPHX1 (0.41) | EPHX1CYP3A4TSHRPPARGPPARD | |
| SCHEMBL3870353 | 0.81 | SLC7A5 (0.50) | EPHX1SOAT1GFERALDH1A1CYP3A4 | |
| SCHEMBL625334 | 0.81 | SLC7A5 (0.50) | EPHX1SOAT1GFERALDH1A1CYP3A4 | |
| SCHEMBL2109313 | 0.80 | EPHX1 (0.68) | EPHX1ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL22937469 | 0.79 | EPHX1 (0.50) | EPHX1SOAT1GFERALDH1A1CYP3A4 | |
| SCHEMBL6892536 | 0.78 | PRSS1 (0.53) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners (US) | 2025-04-01 | — | — | US | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230024240-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-01-26 | — | — | US | disclosed |
| US-20230024240-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-01-26 | — | — | US | disclosed |
| EP-3842420-B1 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS LLC (US) | 2022-12-07 | — | — | EP | disclosed |
| US-5714166-A | Bioactive and/or targeted dendrimer conjugates | THE DOW CHEMICAL COMPANY (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0271180-B2 | Starburst conjugates | DOW CHEMICAL CO (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5527524-A | AGRICULTURAL, PHARMACEUTICAL, DRUG DELIVERY | THE DOW CHEMICAL COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0699079-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1995024221-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5338532-A | Star polymer as carrier for drugs, agricultural compounds | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0271180-A1 | Starburst conjugates | THE DOW CHEMICAL COMPANY (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988001178-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| WO-1988001179-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| WO-1988001180-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024240-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | EPHX1 209/4885SOAT1 1413/4885GFER 2160/4885 |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | EPHX1 209/4885SOAT1 1413/4885GFER 2160/4885 |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | EPHX1 209/4885SOAT1 1413/4885GFER 2160/4885 |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | EPHX1 209/4885SOAT1 1413/4885GFER 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.