SCHEMBL6896247

SCHEMBL6896247

CC[C@H]1C(c2cn3c(C)nc(S(C)(=O)=O)c3s2)=C(C(=O)O)N2C(=O)[C@H]([C@@H](C)O)[C@@H]12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6887322 0.90 CACNA1C (0.35) CACNA1C
SCHEMBL6894605 0.90 CACNA1C (0.35) CACNA1C
SCHEMBL7730797 0.83 ABCC2 (0.32)
SCHEMBL6887107 0.81 CACNA1C (0.35) CACNA1C
SCHEMBL6895013 0.80 CACNA1C (0.34) CACNA1C
SCHEMBL6886789 0.80 CACNA1C (0.34) CACNA1C
SCHEMBL6886105 0.80 KDM4E (0.38)
SCHEMBL6892382 0.79 ESR1 (0.33) CACNA1C
SCHEMBL7729753 0.79 FAP (0.45)
SCHEMBL7634446 0.78 CACNA1C (0.34) CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677331-B2 HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS MEIJI SEIKA KAISHA, LTD. (JP) 2004-01-13 US disclosed