Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.55 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26528807 | 0.89 | NFKB1 (0.72) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL17502354 | 0.85 | RAB9A (0.60) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL6398047 | 0.83 | NFKB1 (0.60) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL6398347 | 0.81 | NFKB1 (0.74) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL2282039 | 0.81 | NFKB1 (0.83) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL9578083 | 0.80 | NFKB1 (0.59) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL7193907 | 0.79 | CYP2D6 (0.57) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL11297508 | 0.79 | NFKB1 (0.70) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL2978651 | 0.79 | NFKB1 (0.66) | NFKB1NFKB2RELACYP19A1SLC5A1 | |
| SCHEMBL29684688 | 0.79 | NFKB1 (0.66) | NFKB1NFKB2RELACYP19A1SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674530-B1 | RADIOLABELED POLYHYDRIC PHENOL COMPOUNDS | MALLINCKRODT INC (US) | 2004-09-01 | — | — | EP | disclosed |
| US-5780008-A | DIAGNOSTIC AGENT FOR INCREASED GLUCOSE METABOLISM AND/OR FOR TUMOR CELLS; RADIOLABELLED DERIVATIVES OF PHLORETIN, GENISTEIN, NARINGENIN AHD PHLORIZIN; RADIOLOGY | MALLINCKRODT MEDICAL, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| US-5741476-A | RADIOLABELLED WITH HALOGEN ISOTOPE; MEDICAL DIAGNOSIS, ANTITUMOR AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1998-04-21 | — | — | US | disclosed |