SCHEMBL6896595

SCHEMBL6896595

C=CCc1ccnc2c(O)cccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.68
LMNA P02545 2/20 0.68
ALOX12 P18054 2/20 0.68
MAPT P10636 2/20 0.68
TP53 P04637 1/20 0.68
TSHR P16473 1/20 0.68
MAOB P27338 3/20 0.52
MAOA P21397 2/20 0.52
L3MBTL1 Q9Y468 3/20 0.50
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
HTT P42858 2/20 0.50
GAA P10253 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4A O75164 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
HIF1AN Q9NWT6 1/20 0.47
PAX8 Q06710 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31106423 0.87 KDM4E (0.68) KDM4ELMNAALOX12MAPTTP53
SCHEMBL6892279 0.87 KDM4E (0.68) KDM4ELMNAALOX12MAPTTP53
SCHEMBL4538975 0.84 KDM4E (0.68) KDM4ELMNAALOX12MAPTTP53
SCHEMBL16132606 0.81 KDM4E (1.00) KDM4ELMNAALOX12MAPTTP53
SCHEMBL1714724 0.78 KDM4E (0.74) KDM4ELMNAALOX12MAPTTP53
SCHEMBL16965245 0.78 KDM4E (0.74) KDM4ELMNAALOX12MAPTTP53
SCHEMBL29203716 0.78 KDM4E (0.74) KDM4ELMNAALOX12MAPTTP53
SCHEMBL11190488 0.76 CDK1 (0.46) KDM4ELMNAALOX12MAPTTP53
SCHEMBL9280481 0.76 KDM4E (0.47) KDM4ELMNAALOX12MAPTTP53
SCHEMBL21409555 0.75 GABRA1 (0.55) KDM4ELMNAALOX12MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499739-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body Mutsubishi Rayon Co., Ltd. (JP) 2016-11-22 US claimed
US-9499739-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body Mutsubishi Rayon Co., Ltd. (JP) 2016-11-22 US disclosed
US-20150299564-A1 THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDING MATERIAL, AND LIGHT-EMITTING BODY MITSUBISHI RAYON CO., LTD. (JP) 2015-10-22 US disclosed
US-9090820-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body MITSUBISHI RAYON CO., LTD. (JP) 2015-07-28 US disclosed
US-20130248765-A1 THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDING MATERIAL, AND LIGHT-EMITTING BODY MITSUBISHI RAYON CO., LTD. (JP) 2013-09-26 US disclosed
US-20040002578-A1 AIRq'2-type aluminum compound and method for manufacturing the same and derivative thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 2004-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002578-A1 AIRq'2-type aluminum compound and method for manufacturing the same and derivative thereof RECQL, ATXN2L, KCNQ2 KDM4E 2028/4885LMNA 4449/4885ALOX12 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.