Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892279 | 0.86 | KDM4E (0.68) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL6280397 | 0.86 | MEN1 (0.54) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL31106423 | 0.86 | KDM4E (0.68) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL11190488 | 0.78 | CDK1 (0.46) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL12533508 | 0.78 | CCR1 (0.53) | KDM4EL3MBTL1HTTLMNAGAA | |
| SCHEMBL9276577 | 0.78 | GABRA1 (0.39) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL17926740 | 0.78 | KDM4E (0.51) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL431328 | 0.78 | MAPT (0.48) | KDM4EL3MBTL1HTTLMNARAB9A | |
| SCHEMBL11846271 | 0.77 | L3MBTL1 (0.47) | KDM4EL3MBTL1NPC1HTTLMNA | |
| SCHEMBL6896595 | 0.76 | KDM4E (0.68) | KDM4EL3MBTL1NPC1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |