Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194134 | 0.94 | MAPT (0.59) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7145763 | 0.88 | ALDH1A1 (0.54) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL6774065 | 0.87 | ALDH1A1 (0.55) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5878110 | 0.86 | ALDH1A1 (0.54) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12317324 | 0.84 | GAA (0.56) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3837360 | 0.83 | ALDH1A1 (0.54) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7146586 | 0.82 | ALDH1A1 (0.73) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7410768 | 0.82 | ITGB3 (0.54) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5878081 | 0.82 | ITGB3 (0.54) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3834077 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833366-B1 | Dihydrostilbene alkanoic acid derivatives | PHARMACIA CORPORATION | 2004-12-21 | — | — | US | disclosed |
| EP-1289959-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096310-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |