Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 3/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896957 | 0.99 | LTA4H (0.40) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL6897170 | 0.97 | LTA4H (0.42) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL6894998 | 0.97 | LTA4H (0.42) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL6897064 | 0.97 | LTA4H (0.42) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL6897260 | 0.96 | MCHR1 (0.35) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL6897605 | 0.89 | LTA4H (0.41) | LTA4HMCHR1CASRMMEPOLB | |
| SCHEMBL27541778 | 0.83 | METAP2 (0.35) | MCHR1CASRHRH3METAP2 | |
| SCHEMBL6891339 | 0.83 | LTA4H (0.35) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL27576389 | 0.83 | LTA4H (0.35) | LTA4HMCHR1CASRMMEHRH3 | |
| SCHEMBL6896637 | 0.82 | LTA4H (0.37) | LTA4HMCHR1CASRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730784-B2 | AS THERAPEUTIC AGENTS FOR AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | LTA4H 411/4885MCHR1 1236/4885CASR 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.