Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | NPY2R | P49146 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901821 | 0.95 | MCHR1 (0.44) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6901688 | 0.94 | MCHR1 (0.46) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6901950 | 0.93 | MCHR1 (0.44) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6902446 | 0.92 | NPY2R (0.47) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL7054601 | 0.92 | MCHR1 (0.43) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6902524 | 0.92 | MCHR1 (0.46) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6902620 | 0.91 | MCHR1 (0.42) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6896762 | 0.90 | MAPT (0.44) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6052503 | 0.87 | SMN1; SMN2 (0.53) | MAPTHTTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL6901167 | 0.87 | MCHR1 (0.44) | MAPTHTTKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |