Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901167 | 0.94 | MCHR1 (0.44) | MCHR1EPHX2ACP1HTTKMT2A | |
| SCHEMBL6897156 | 0.93 | MAPT (0.46) | MCHR1EPHX2FGFR1HTTKMT2A | |
| SCHEMBL6901821 | 0.91 | MCHR1 (0.44) | MCHR1EPHX2FGFR1HTTKMT2A | |
| SCHEMBL6895056 | 0.90 | MAPT (0.43) | MCHR1FGFR1ACP1MAPTEGFR | |
| SCHEMBL6902524 | 0.90 | MCHR1 (0.46) | MCHR1EPHX2FGFR1HTTKMT2A | |
| SCHEMBL7054601 | 0.90 | MCHR1 (0.43) | MCHR1EPHX2FGFR1HTTKMT2A | |
| SCHEMBL6902620 | 0.89 | MCHR1 (0.42) | MCHR1EPHX2FGFR1HTTKMT2A | |
| SCHEMBL6896762 | 0.88 | MAPT (0.44) | MCHR1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6052252 | 0.88 | MCHR1 (0.46) | MCHR1EPHX2FGFR1HTTKMT2A | |
| Water SCHEMBL6052454 | 0.87 | MCHR1 (0.45) | MCHR1EPHX2FGFR1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |