Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901971 | 0.91 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6897156 | 0.90 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6052387 | 0.88 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6901821 | 0.88 | MCHR1 (0.44) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6901950 | 0.88 | MCHR1 (0.44) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL7054601 | 0.87 | MCHR1 (0.43) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6902524 | 0.87 | MCHR1 (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL6902620 | 0.86 | MCHR1 (0.42) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL6901688 | 0.86 | MCHR1 (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6901167 | 0.84 | MCHR1 (0.44) | MAPTSMN1; SMN2MAPK1LMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |