Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897156 | 0.94 | MAPT (0.46) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6901167 | 0.93 | MCHR1 (0.44) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6902788 | 0.92 | MCHR1 (0.45) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL7059080 | 0.92 | MCHR1 (0.43) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6902429 | 0.91 | MCHR1 (0.43) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6901821 | 0.88 | MCHR1 (0.44) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6901950 | 0.87 | MCHR1 (0.44) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6052110 | 0.86 | SMN1; SMN2 (0.50) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6896762 | 0.86 | MAPT (0.44) | MCHR1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL7055517 | 0.86 | ALDH1A1 (0.41) | MCHR1MAPTKMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |