SCHEMBL6897374

SCHEMBL6897374

[O]CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6897341 1.00 TSHR (0.39) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL10638134 0.97 TSHR (0.37) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL21425 0.90 TSHR (0.38) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL1434283 0.81 TSHR (0.37) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL1535903 0.81 THRB (0.30)
SCHEMBL3919509 0.80 TSHR (0.36) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL30096012 0.80 TSHR (0.36) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL30095977 0.80 TSHR (0.36) TSHRUSP2MAPTKDM4ETDP1
SCHEMBL186999 0.78 KDM4E (0.31) TSHRKDM4ETDP1
SCHEMBL1824897 0.78 TSHR (0.42) TSHRUSP2MAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699557-B2 Optical recording medium and optical recording method TDK CORPORATION (JP) 2004-03-02 US disclosed
US-20020192423-A1 Optical recording medium and optical recording method TDK CORPORATION (JP) 2002-12-19 US disclosed
EP-1246175-A2 Optical recording medium and optical recording method TDK Corporation (JP) 2002-10-02 EP disclosed
US-5536548-A PHTHALOCYANINE DYE AND A SECOND DYE WITH A LOWER HEAT DECOMPOSITION TEMPERATURE TDK CORPORATION (JP) 1996-07-16 US disclosed
EP-0623923-A1 Optical recording medium TOYO INK MANUFACTURING CO., LTD. (JP) 1994-11-09 EP disclosed
US-5348840-A Optical recording medium TOYO INK MANUFACTURING CO., LTD. (JP) 1994-09-20 US disclosed
US-5248339-A Polyfluoropolyphazenes EASTMAN KODAK COMPANY (US) 1993-09-28 US disclosed
US-3938999-A SURFACE ACTIVE ADDITION COPOLYMER FUJI PHOTO FILM CO., LTD. (JA) 1976-02-17 US disclosed