Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25684960 | 0.82 | USP2 (0.34) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL25685793 | 0.82 | USP2 (0.34) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL25685790 | 0.82 | USP2 (0.34) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL25685791 | 0.82 | USP2 (0.34) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL6897374 | 0.81 | TSHR (0.39) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL6897341 | 0.81 | TSHR (0.39) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL25761903 | 0.79 | TSHR (0.32) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL17312039 | 0.79 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL25761873 | 0.78 | USP2 (0.33) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL10638134 | 0.78 | TSHR (0.37) | TSHRUSP2MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220362161-A1 | COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME | VARIAN MEDICAL SYSTEMS, INC. | 2022-11-17 | — | — | US | claimed |
| US-11426355-B2 | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | VARIAN MEDICAL SYSTEMS, INC. (US) | 2022-08-30 | — | — | US | claimed |
| US-20210023015-A1 | COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME | CELANOVA BIOSCIENCES, INC. | 2021-01-28 | — | — | US | claimed |
| US-20220362161-A1 | COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME | VARIAN MEDICAL SYSTEMS, INC. | 2022-11-17 | — | — | US | disclosed |
| US-11426355-B2 | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | VARIAN MEDICAL SYSTEMS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20210290555-A1 | LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME | CELONOVA BIOSCIENCES GERMANY GMBH (DE) | 2021-09-23 | — | — | US | disclosed |
| US-11052050-B2 | Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | VARIAN MEDICAL SYSTEMS, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-10973770-B2 | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | VARIAN MEDICAL SYSTEMS, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20210023015-A1 | COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME | CELANOVA BIOSCIENCES, INC. | 2021-01-28 | — | — | US | disclosed |
| US-20170172933-A1 | LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME | VARIAN MEDICAL SYSTEMS, INC. | 2017-06-22 | — | — | US | disclosed |
| US-9597419-B2 | Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same | BOSTON SCIENTIFIC LIMITED (BM) | 2017-03-21 | — | — | US | disclosed |
| US-20080138377-A1 | Vasodilator Eluting Luminal Stent Devices With A Specific Polyphosphazene Coating and Methods for Their Manufacture and Use | CELONOVA BIOSCIENCES, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080138433-A1 | VASODILATOR ELUTING BLOOD STORAGE AND ADMINISTRATION DEVICES WITH A SPECIFIC POLYPHOSPHAZENE COATING AND METHODS FOR THEIR MANUFACTURE AND USE | CELONOVA BIOSCIENCES, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080113029-A1 | Color-Coded and Sized Loadable Polymeric Particles for Therapeutic and/or Diagnostic Applications and Methods of Preparing and Using the Same | CELONOVA BIOSCIENCES, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080102029-A1 | Loadable Polymeric Particles For Enhanced Imaging In Clinical Applications And Methods Of Preparing And Using The Same | CELONOVA BIOSCIENCES, INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080095816-A1 | Medical device for introduction into human or animal body or organ, or which has contact with tissue or fluids of human or animal body or organ, comprising a polyorganosiloxane and one or more polyphosphazenes; combination of materials has been found to render device more biocompatible, antithrombogenic | CELONOVA BIOSCIENCES, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008045953-A2 | COMPOSITIONS AND DEVICES COMRISING SILICONE AND SPECIFIC POLYPHOSPHAZENES | CELONOVA BIOSCIENCES, INC. (US) | 2008-04-17 | — | — | WO | disclosed |
| EP-1804773-A2 | LOADABLE POLYPHOSPHAZENE-COMPRISING PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME | Polyzenix GmbH (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006046155-A2 | LOADABLE POLYPHOSPHAZENE-COMPRISING PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME | POLYZENIX GMBH (DE) | 2006-05-04 | — | — | WO | disclosed |
| US-20060088476-A1 | Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | POLYZENIX GMBH (DE) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210290555-A1 | LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME | PIGS, PHOSPHO1, PF4 | TSHR 160/4885USP2 189/4885MAPT 3802/4885 |
| US-20080113029-A1 | Color-Coded and Sized Loadable Polymeric Particles for Therapeutic and/or Diagnostic Applications and Methods of Preparing and Using the Same | PHOSPHO1, HPSE, CHMP4B | TSHR 1279/4885USP2 184/4885MAPT 2739/4885 |
| US-11426355-B2 | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | PHOSPHO1, HPSE, MTDH | TSHR 1200/4885USP2 202/4885MAPT 3015/4885 |
| US-20060088476-A1 | Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | PIGS, PHOSPHO1, PF4 | TSHR 160/4885USP2 189/4885MAPT 3802/4885 |
| US-20170172933-A1 | LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME | PIGS, PHOSPHO1, PF4 | TSHR 160/4885USP2 189/4885MAPT 3802/4885 |
| US-20080138377-A1 | Vasodilator Eluting Luminal Stent Devices With A Specific Polyphosphazene Coating and Methods for Their Manufacture and Use | PTGIR, PDE3B, PDE2A | TSHR 2867/4885USP2 1284/4885MAPT 4122/4885 |
| US-11052050-B2 | Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | PIGS, PHOSPHO1, PF4 | TSHR 141/4885USP2 177/4885MAPT 4014/4885 |
| US-20080102029-A1 | Loadable Polymeric Particles For Enhanced Imaging In Clinical Applications And Methods Of Preparing And Using The Same | PHOSPHO1, FGB, HPSE | TSHR 431/4885USP2 326/4885MAPT 3434/4885 |
| US-20220362161-A1 | COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME | PHOSPHO1, ALPP, HPSE | TSHR 2141/4885USP2 329/4885MAPT 3066/4885 |
| US-20080138433-A1 | VASODILATOR ELUTING BLOOD STORAGE AND ADMINISTRATION DEVICES WITH A SPECIFIC POLYPHOSPHAZENE COATING AND METHODS FOR THEIR MANUFACTURE AND USE | PTGIR, TNNT2, TNNI3 | TSHR 1673/4885USP2 962/4885MAPT 3668/4885 |
| US-20210023015-A1 | COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME | PHOSPHO1, ALPP, HPSE | TSHR 2141/4885USP2 329/4885MAPT 3066/4885 |
| US-10973770-B2 | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same | PHOSPHO1, HPSE, MTDH | TSHR 1200/4885USP2 202/4885MAPT 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.