Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.65 |
| ▸ | XDH | P47989 | 6/20 | 0.65 |
| ▸ | PPARG | P37231 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | CA12 | O43570 | 4/20 | 0.65 |
| ▸ | CA7 | P43166 | 4/20 | 0.65 |
| ▸ | IPMK | Q8NFU5 | 4/20 | 0.65 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.65 |
| ▸ | CA4 | P22748 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21096931 | 0.85 | ABCB1 (0.56) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL30255771 | 0.85 | ABCB1 (1.00) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL4034698 | 0.85 | ABCB1 (1.00) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL21798840 | 0.84 | CYP1A2 (0.65) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| Syringetin SCHEMBL29929167 | 0.82 | ABCB1 (0.85) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| Syringetin SCHEMBL810981 | 0.82 | ABCB1 (0.85) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL4649099 | 0.82 | TUBB4A (0.70) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| SCHEMBL31675780 | 0.82 | TUBB4A (0.70) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| Laricytrin SCHEMBL19213534 | 0.81 | ABCB1 (0.83) | ABCB1CYP1A1CYP1A2CYP1B1XDH | |
| Laricytrin SCHEMBL29929477 | 0.81 | ABCB1 (0.83) | ABCB1CYP1A1CYP1A2CYP1B1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242503-A1 | Compositions comprising blockers of l-dopa renal cell transfer for the treatment of parkinson's disease | ATTENTION LABS INCORPORATED | 2004-12-02 | — | — | US | claimed |
| EP-1267853-B1 | COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE | PORTELA & CA SA (PT) | 2004-09-08 | — | — | EP | claimed |
| EP-1267853-A2 | COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE | Portela & Ca., S.A. (PT) | 2003-01-02 | — | — | EP | claimed |
| WO-2001068065-A9 | COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE | PORTELA & CA SA (PT) | 2002-07-18 | — | — | WO | claimed |
| WO-2001068065-A2 | COMPOSITIONS COMPRISING BLOCKERS OF L-DOPA RENAL CELL TRANSFER FOR THE TREATMENT OF PARKINSON'S DISEASE | PORTELA & COMPANHIA S.A. (PT) | 2001-09-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242503-A1 | Compositions comprising blockers of l-dopa renal cell transfer for the treatment of parkinson's disease | COMT, DDC, AADAT | ABCB1 54/4885CYP1A1 1911/4885CYP1A2 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.