Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.44 |
| ▸ | METAP1 | P53582 | 4/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898450 | 1.00 | METAP2 (0.44) | METAP2METAP1EPHX1KDM4EMEN1 | |
| SCHEMBL6897426 | 0.77 | METAP2 (0.49) | METAP2METAP1EPHX1ACP3 | |
| SCHEMBL6897414 | 0.77 | METAP2 (0.49) | METAP2METAP1EPHX1ACP3 | |
| SCHEMBL6898544 | 0.76 | IDO1 (0.42) | METAP2METAP1KDM4EMEN1KMT2A | |
| SCHEMBL6898546 | 0.76 | IDO1 (0.42) | METAP2METAP1KDM4EMEN1KMT2A | |
| SCHEMBL6899688 | 0.76 | IDO1 (0.42) | METAP2METAP1KDM4EMEN1KMT2A | |
| SCHEMBL6896230 | 0.75 | GABBR2 (0.45) | METAP2METAP1EPHX1KDM4EMEN1 | |
| SCHEMBL6896239 | 0.75 | GABBR2 (0.45) | METAP2METAP1EPHX1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6898738 | 0.74 | IDO1 (0.44) | METAP2METAP1KDM4EMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL6898731 | 0.74 | IDO1 (0.44) | METAP2METAP1KDM4EMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317461-B1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1317461-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6509472-B2 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2003-01-21 | — | — | US | disclosed |
| WO-2002022623-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |