Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17565146 | 0.98 | SLC6A3 (0.54) | SLC6A3DRD2SLC6A4HTTMAOA | |
| SCHEMBL13569151 | 0.90 | MAOA (0.59) | SLC6A3DRD2SLC6A4HTTMAOA | |
| SCHEMBL4321331 | 0.84 | SLC6A3 (0.50) | SLC6A3DRD2SLC6A4MAOAMAOB | |
| SCHEMBL22201773 | 0.82 | SLC6A3 (0.51) | SLC6A3DRD2SLC6A4HTTMAOA | |
| SCHEMBL2197339 | 0.81 | SLC18A3 (0.46) | — | |
| SCHEMBL18976829 | 0.81 | NPC1 (0.51) | TAAR1ALDH1A1 | |
| SCHEMBL16191197 | 0.80 | ALDH1A1 (0.50) | SLC6A3DRD2SLC6A4HTTTAAR1 | |
| SCHEMBL2440428 | 0.79 | SLC18A3 (0.60) | MAOAMAOB | |
| SCHEMBL9133642 | 0.79 | SLC18A3 (0.60) | MAOAMAOB | |
| SCHEMBL7419921 | 0.79 | SLC18A3 (0.60) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026143-B1 | NOVEL LIQUID-CRYSTAL COMPOUNDS HAVING LARGE NEGATIVE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORP (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-20020030179-A1 | NOVEL LIQUID-CRYSTAL COMPOUNDS HAVING LARGE NEGATIVE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | JNC CORPORATION (JP) | 2002-03-14 | — | — | US | disclosed |
| US-6348244-B1 | COMPOUNDS HAVING 2,3-DIFLUOROPHENYL MOIETY; IN-PLANE SWITCHING DISPLAY DEVICES; VERTICAL ALIGNMENT CELLS | CHISSO CORPORATION (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1026143-A1 | NOVEL LIQUID-CRYSTAL COMPOUNDS HAVING LARGE NEGATIVE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-08-09 | — | — | EP | disclosed |