SCHEMBL6897816

SCHEMBL6897816

C=CCc1cc(O)c2ncccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.49
L3MBTL1 Q9Y468 8/20 0.49
NPC1 O15118 7/20 0.49
RAB9A P51151 6/20 0.49
COMT P21964 2/20 0.47
MMP2 P08253 1/20 0.47
CHRM1 P11229 1/20 0.47
TSHR P16473 1/20 0.47
ADRA1A P35348 1/20 0.47
METAP2 P50579 1/20 0.47
METAP1 P53582 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PKM P14618 1/20 0.47
NFKB1 P19838 1/20 0.47
HTT P42858 1/20 0.47
CASP6 P55212 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7437842 0.81 LMNA (0.44) KDM4EL3MBTL1NPC1RAB9AMMP2
SCHEMBL686939 0.79 KDM4E (0.53) KDM4EL3MBTL1NPC1RAB9ACOMT
SCHEMBL15217635 0.79 KDM4E (0.53) KDM4EL3MBTL1NPC1RAB9ACOMT
SCHEMBL6895662 0.78 KDM4E (0.53) KDM4ECOMTMMP2CHRM1TSHR
SCHEMBL23928250 0.76 KDM4E (0.53) KDM4EL3MBTL1NPC1RAB9ACOMT
SCHEMBL15217628 0.75 KDM4E (0.56) KDM4EL3MBTL1NPC1RAB9ACOMT
SCHEMBL3432556 0.75 KDM4E (0.52) KDM4EL3MBTL1NPC1RAB9ACOMT
SCHEMBL20122351 0.75 KDM4E (0.49) KDM4EL3MBTL1NPC1RAB9ACOMT
SCHEMBL21409562 0.73 XDH (0.52) KDM4EMAPTXDHGAATNKS
Oxyquinoline SCHEMBL904365 0.72 TSHR (0.72) KDM4EL3MBTL1NPC1RAB9ACOMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499739-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body Mutsubishi Rayon Co., Ltd. (JP) 2016-11-22 US claimed
CN-113571652-A Light-emitting device, metal complex, light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2021-10-29 CN disclosed
US-9499739-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body Mutsubishi Rayon Co., Ltd. (JP) 2016-11-22 US disclosed
US-20150299564-A1 THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDING MATERIAL, AND LIGHT-EMITTING BODY MITSUBISHI RAYON CO., LTD. (JP) 2015-10-22 US disclosed
US-9090820-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body MITSUBISHI RAYON CO., LTD. (JP) 2015-07-28 US disclosed
US-20130248765-A1 THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDING MATERIAL, AND LIGHT-EMITTING BODY MITSUBISHI RAYON CO., LTD. (JP) 2013-09-26 US disclosed
US-20040002578-A1 AIRq'2-type aluminum compound and method for manufacturing the same and derivative thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 2004-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002578-A1 AIRq'2-type aluminum compound and method for manufacturing the same and derivative thereof RECQL, ATXN2L, KCNQ2 KDM4E 2028/4885L3MBTL1 3007/4885NPC1 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.