Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.32 |
| ▸ | MMP8 | P22894 | 11/20 | 0.32 |
| ▸ | MMP9 | P14780 | 10/20 | 0.32 |
| ▸ | MMP1 | P03956 | 13/20 | 0.32 |
| ▸ | MMP3 | P08254 | 7/20 | 0.31 |
| ▸ | MMP7 | P09237 | 4/20 | 0.31 |
| ▸ | FCER2 | P06734 | 1/20 | 0.31 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.31 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | MMP15 | P51511 | 1/20 | 0.31 |
| ▸ | MMP16 | P51512 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.31 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.31 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890608 | 0.89 | MME (0.39) | — | |
| Hydrochloric Acid SCHEMBL6889416 | 0.88 | MME (0.38) | — | |
| SCHEMBL6896565 | 0.87 | — | — | |
| SCHEMBL27562651 | 0.78 | MMP1 (0.50) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL6899001 | 0.78 | MMP1 (0.50) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL18676429 | 0.76 | CTSS (0.35) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL3834639 | 0.75 | MMP1 (0.32) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL6898877 | 0.74 | MMP1 (0.55) | MMP2MMP8MMP9MMP1MMP3 | |
| SCHEMBL6897261 | 0.73 | MMP1 (0.46) | MMP2MMP1MMP3FCER2 | |
| SCHEMBL27543456 | 0.73 | MMP1 (0.52) | MMP2MMP8MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730784-B2 | AS THERAPEUTIC AGENTS FOR AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | MMP2 3359/4885MMP8 3131/4885MMP9 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.