Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.53 |
| ▸ | CTSL | P07711 | 7/20 | 0.36 |
| ▸ | CTSS | P25774 | 7/20 | 0.36 |
| ▸ | CTSB | P07858 | 5/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686403 | 0.89 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7424532 | 0.88 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096677 | 0.85 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4687353 | 0.85 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7165219 | 0.82 | CTSK (0.38) | CTSKPKMMEN1KMT2A | |
| SCHEMBL7426096 | 0.80 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7428434 | 0.79 | MEN1 (0.48) | PKMMEN1KMT2A | |
| SCHEMBL7538673 | 0.78 | ATM (0.49) | — | |
| SCHEMBL5092893 | 0.77 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5099002 | 0.77 | CTSK (0.41) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | claimed |
| EP-1232154-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1232154-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2001034600-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |