Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897943 | 1.00 | TSHR (0.55) | TSHRMAPTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL6900741 | 1.00 | TSHR (0.55) | TSHRMAPTKMT2ASMN1; SMN2TDP1 | |
| Acetic Acid SCHEMBL10333511 | 0.95 | TSHR (0.50) | TSHRMAPTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL6902376 | 0.81 | GSK3B (0.48) | MAPTKMT2ASMN1; SMN2MEN1CES1 | |
| SCHEMBL6900441 | 0.81 | GSK3B (0.50) | MAPTKMT2ACES1PDPK1NPC1 | |
| SCHEMBL6904340 | 0.81 | GSK3B (0.50) | MAPTKMT2ACES1PDPK1NPC1 | |
| SCHEMBL6902380 | 0.81 | GSK3B (0.48) | MAPTKMT2ASMN1; SMN2MEN1CES1 | |
| SCHEMBL16324477 | 0.81 | TSHR (0.55) | TSHRMAPTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL8900391 | 0.81 | TSHR (0.55) | TSHRMAPTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL8900386 | 0.81 | TSHR (0.55) | TSHRMAPTKMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833468-B2 | Reacting an optically active imine with a compound that is a hemiacetal of a perfluoroalkylaldehyde or a hydrate of a perfluoroalkylaldehyde to obtain a condensate, hydrolyzing | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-12-21 | — | — | US | claimed |
| EP-0327349-A2 | Liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-08-09 | — | — | EP | claimed |
| JP-1246239-A | — | — | None | — | — | JP | disclosed |
| JP-3176450-A | — | — | None | — | — | JP | disclosed |
| JP-3176450-A | — | — | None | — | — | JP | disclosed |
| US-6833468-B2 | Reacting an optically active imine with a compound that is a hemiacetal of a perfluoroalkylaldehyde or a hydrate of a perfluoroalkylaldehyde to obtain a condensate, hydrolyzing | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-12-21 | — | — | US | disclosed |
| US-6642409-B2 | Reacting an imine with a hemiacetal; hydrolysis under acid conditions | CENTRAL GLASS COMPANY, LIMITED (JP) | 2003-11-04 | — | — | US | disclosed |
| US-6639100-B2 | Baeyer-Villiger oxidation of an optically active 4,4,4-tri-fluoro-3-hydroxy-1-aryl-1-butanone; purification by precipitation and removing racemic crystals; agriculture; drugs; ferroelectric liquid crystals; chemical intermediates | CENTRAL GLASS COMPANY, LIMITED (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20030100767-A1 | Reacting an optically active imine with a compound that is a hemiacetal of a perfluoroalkylaldehyde or a hydrate of a perfluoroalkylaldehyde to obtain a condensate, hydrolyzing | CENTRAL GLASS COMPANY, LIMITED | 2003-05-29 | — | — | US | disclosed |
| US-20030088095-A1 | Reacting an optically active imine with a hemiacetal of a perfluoroalkylaldehyde or a hydrate; hydrolyzing the condensate under an acid condition. | CENTRAL GLASS COMPANY, LIMITED | 2003-05-08 | — | — | US | disclosed |
| US-20020016511-A1 | Reacting an imine with a hemiacetal; hydrolysis under acid conditions | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-02-07 | — | — | US | disclosed |
| US-5424005-A | Fluoroalkyl group containing benzoic acid esters | SHOWA SHELL SEKIYU K.K. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5204020-A | For display elements or an electrooptical element | SHOWA SHELL SEKIYU K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| JP-H03176450-A | PRODUCTION OF 3-HYDROXY-4,4,4-TRIFLUORO-1-PHENYLBUTAN-1-ONE | TOAGOSEI CHEM IND CO LTD | 1991-07-31 | — | — | JP | disclosed |
| JP-H03176450-A | PRODUCTION OF 3-HYDROXY-4,4,4-TRIFLUORO-1-PHENYLBUTAN-1-ONE | TOAGOSEI CHEM IND CO LTD | 1991-07-31 | — | — | JP | disclosed |
| US-4929760-A | ENANTIOMORPHS, LIQUID CRYSTALS, FUNGICIDES, HERBICIDES | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1990-05-29 | — | — | US | disclosed |
| JP-H01246239-A | FLUORINE-CONTAINING CARBONYL COMPOUND AND PRODUCTION THEREOF | SHOWA SHELL SEKIYU KK | 1989-10-02 | — | — | JP | disclosed |
| EP-0327349-A2 | Liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100767-A1 | Reacting an optically active imine with a compound that is a hemiacetal of a perfluoroalkylaldehyde or a hydrate of a perfluoroalkylaldehyde to obtain a condensate, hydrolyzing | ADH1C, ADH1A, HPD | TSHR 1837/4885MAPT 2950/4885KMT2A 4162/4885 |
| US-20030088095-A1 | Reacting an optically active imine with a hemiacetal of a perfluoroalkylaldehyde or a hydrate; hydrolyzing the condensate under an acid condition. | ADH1C, ADH1A, HPD | TSHR 1989/4885MAPT 2905/4885KMT2A 4098/4885 |
| US-20020016511-A1 | Reacting an imine with a hemiacetal; hydrolysis under acid conditions | ADH1C, ADH1A, HPD | TSHR 2490/4885MAPT 2961/4885KMT2A 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.