Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28676134 | 0.89 | TSHR (0.61) | TSHRDAONAPRTCES2CES1 | |
| Benzophenone SCHEMBL27611611 | 0.86 | ALDH1A1 (0.66) | SRD5A2ALDH1A1EGFRHPGDPGR | |
| Benzoic Acid SCHEMBL1463186 | 0.86 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2400344 | 0.85 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9705228 | 0.85 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28601772 | 0.85 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28693411 | 0.85 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1110868 | 0.85 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| N,N-Dimethylethanaminium SCHEMBL27712526 | 0.84 | ALDH1A1 (0.48) | TSHRCES2CES1ALDH1A1EGFR | |
| Benzoic Acid SCHEMBL7547475 | 0.84 | TSHR (0.61) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874915-A | Silane self-crosslinking low-smoke halogen-free polyolefin cable material and preparation method thereof | 廊坊崔氏电缆材料股份有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-114672322-A | PDLC light modulation material, light modulation film and preparation method of light modulation film | 深圳市高仁电子新材料有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-113652181-A | Novel UV (ultraviolet) viscosity-reducing adhesive and preparation method thereof | 深圳市高仁电子新材料有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-113604171-A | Black optical cement and preparation method thereof | 深圳市高仁电子新材料有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113249039-A | Optical adhesive | 广西向东电子科技有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-111944455-A | High-weather-resistance blue-light-proof optical adhesive and film forming preparation method thereof | 深圳市高仁电子新材料有限公司 | 2020-11-17 | — | — | CN | claimed |
| JP-4037112-A | — | — | None | — | — | JP | disclosed |
| US-20240009357-A1 | 3D PRINTING OF BIOMEDICAL IMPLANTS | NORTHWESTERN UNIVERSITY | 2024-01-11 | — | — | US | disclosed |
| CN-116874915-A | Silane self-crosslinking low-smoke halogen-free polyolefin cable material and preparation method thereof | 廊坊崔氏电缆材料股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116855954-A | Method for cleaning developing tank or film stripping tank | 立讯精密工业（滁州）有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116560132-A | Preparation method of high-transmittance low-haze dimming film | 佛山辰威新材料科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-3959247-B1 | LOW VISCOSITY CROSSLINKABLE COMPOSITIONS FOR COATINGS AND MATERIALS WITH A HIGH REFRACTIVE INDEX AND HIGH THERMAL DEFLECTION TEMPERATURE | ARKEMA FRANCE (FR) | 2023-04-19 | — | — | EP | disclosed |
| CN-115974846-A | Synthetic method and application of organic dye fluorescent small molecule material | 深圳职业技术学院 | 2023-04-18 | — | — | CN | disclosed |
| EP-0798590-A2 | Liquid crystal display element with a transparent electrode substrate, and the transparent electrode substrate | TEIJIN LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0432907-B1 | Improved paste compositions | JOHNSON MATTHEY PLC (GB) | 1995-05-17 | — | — | EP | disclosed |
| US-5173457-A | Low-temperature firing of a thick film comprising a binder and dielectric glass particles prepared by a gel-sol method; printed circuits; photoresists | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1992-12-22 | — | — | US | disclosed |
| JP-H0437112-A | ELECTROLYTE FOR ELECTROLYTIC CAPACITOR | ELNA CO LTD | 1992-02-07 | — | — | JP | disclosed |
| EP-0432907-A1 | Improved paste compositions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1991-06-19 | — | — | EP | disclosed |
| US-4925773-A | PHOTOCURABLE RESIN | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0273729-A2 | Solder resist ink composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1988-07-06 | — | — | EP | disclosed |