Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067933 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EHTR2AHRH1TDP1 | |
| SCHEMBL11778053 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EHTR2AHRH1TDP1 | |
| SCHEMBL1936243 | 0.79 | CYP2D6 (0.43) | ALDH1A1KDM4ETDP1CYP2D6LMNA | |
| SCHEMBL27758907 | 0.79 | HTR2A (0.41) | ALDH1A1HTR2AHRH1TDP1CYP2D6 | |
| SCHEMBL27727123 | 0.78 | ESR1 (0.43) | ALDH1A1KDM4ETDP1CYP2D6LMNA | |
| SCHEMBL9276858 | 0.78 | ADRB2 (0.40) | TDP1LMNAMAPTAOC3 | |
| SCHEMBL7743421 | 0.78 | AOC3 (0.39) | ALDH1A1KMT2AAOC3 | |
| SCHEMBL290984 | 0.77 | LMNA (0.46) | ALDH1A1KDM4EHTR2AHRH1TDP1 | |
| SCHEMBL903868 | 0.77 | HTR2A (0.42) | ALDH1A1HTR2AHRH1TDP1CYP2D6 | |
| SCHEMBL3344466 | 0.77 | HTR2A (0.42) | ALDH1A1HTR2AHRH1TDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072486-B | As the connection-1H-benzoglyoxaline of hepatitis C virus inhibitors | SQUIBB BRISTOL MYERS CO. (US) | 2016-04-06 | — | — | CN | claimed |
| CN-102448956-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | claimed |
| CN-101558059-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-12-03 | — | — | CN | claimed |
| CN-101528232-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-11-12 | — | — | CN | claimed |
| CN-102712628-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-15 | — | — | CN | claimed |
| CN-104072486-A | BI-1H-BENZIMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO | 2014-10-01 | — | — | CN | claimed |
| CN-102177141-B | bis-1H-benzimidazoles as hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | claimed |
| CN-102712623-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-04-02 | — | — | CN | claimed |
| CN-102007122-B | Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2013-09-04 | — | — | CN | claimed |
| CN-102712623-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | claimed |
| CN-102712628-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | claimed |
| CN-102448956-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-09 | — | — | CN | claimed |
| CN-102177141-A | bis-1H-benzimidazoles as hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-09-07 | — | — | CN | claimed |
| CN-102007122-A | Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-04-06 | — | — | CN | claimed |
| CN-101558059-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | CN | claimed |
| CN-101528232-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-09-09 | — | — | CN | claimed |
| EP-2049522-A2 | HEPATITIS C VIRUS INHIBITORS | Brystol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008021927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-21 | — | — | WO | claimed |
| CN-104447707-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2017-04-12 | — | — | CN | disclosed |
| WO-2007124345-A2 | BETA-AMYLOID PET IMAGING AGENTS | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2007-11-01 | — | — | WO | disclosed |