Terephthalic Acid

Terephthalic Acid

SCHEMBL753918

O=C(O)c1ccc(C(=O)O)cc1.O=C(O)c1cccc(C(=O)O)c1.OCCO

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
DAO P14920 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA6 P23280 1/20 0.56
CA9 Q16790 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
TP53 P04637 1/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
SRD5A2 P31213 1/20 0.54
FOLH1 Q04609 1/20 0.53
KMO O15229 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL27677452 1.00 TSHR (0.56) TSHRDAONAPRTCA12CA1
Isophthalic Acid SCHEMBL3867184 0.95 CA12 (0.60) TSHRDAONAPRTCA12CA1
Isophthalic Acid SCHEMBL27698835 0.93 CA12 (0.58) TSHRDAONAPRTCA12CA1
Terephthalic Acid SCHEMBL5631843 0.91 TSHR (0.52) TSHRDAONAPRTCA12CA1
Isophthalic Acid SCHEMBL11781611 0.91 CA12 (0.56) TSHRDAONAPRTCA12CA1
Terephthalic Acid SCHEMBL184129 0.91 TSHR (0.68) TSHRDAONAPRTCA12CA1
Terephthalic Acid SCHEMBL4872836 0.91 TSHR (0.68) TSHRDAONAPRTCA12CA1
Terephthalic Acid SCHEMBL10927557 0.91 TSHR (0.68) TSHRDAONAPRTCA12CA1
Terephthalic Acid SCHEMBL6898217 0.90 TSHR (0.50) TSHRDAONAPRTCA12CA1
Terephthalic Acid SCHEMBL9055614 0.89 KMT2A (0.46) TSHRDAONAPRTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-218665858-U Composite flexible film 浙江柔震科技有限公司 2023-03-21 CN claimed
US-3948839-A CROSSLINKED NYLON OR POLYESTER UNIFILM CORPORATION (US) 1976-04-06 US claimed
CN-119894960-A Method for producing polyester film using biomass-derived polyester resin, and polyester film 东洋纺株式会社 2025-04-25 CN disclosed
US-20240157722-A1 DECORATIVE SHEET AND DECORATIVE MEMBER DAI NIPPON PRINTING CO., LTD. (JP) 2024-05-16 US disclosed
US-20240157668-A1 DECORATIVE SHEET AND DECORATIVE MEMBER DAI NIPPON PRINTING CO., LTD. (JP) 2024-05-16 US disclosed
WO-2024071126-A1 DECORATIVE SHEET AND DECORATIVE MATERIAL 大日本印刷株式会社 2024-04-04 WO disclosed
WO-2024070900-A1 DECORATIVE SHEET 大日本印刷株式会社 2024-04-04 WO disclosed
EP-4316812-A1 DECORATIVE SHEET AND DECORATIVE MATERIAL Dai Nippon Printing Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-4316811-A1 COSMETIC SHEET AND COSMETIC MATERIAL Dai Nippon Printing Co., Ltd. (JP) 2024-02-07 EP disclosed
WO-2023233984-A1 RESIN COMPOSITION 三菱瓦斯化学株式会社 2023-12-07 WO disclosed
CN-117083175-A Extinction article 大日本印刷株式会社 2023-11-17 CN disclosed
CN-1047828-A The laminated plate that metal and polyester film constitute GMB FOODCAN PLC (GB) 1990-12-19 CN disclosed
WO-1990014948-A1 LAMINATES OF METAL AND POLYESTER FILM CMB FOODCAN PLC (GB) 1990-12-13 WO disclosed
WO-1990014901-A1 METHOD AND APPARATUS FOR FORMING WALL IRONED ARTICLES CMB FOODCAN PLC (GB) 1990-12-13 WO disclosed
EP-0402006-A1 Method and apparatus for forming wall ironed articles CarnaudMetalbox plc (GB) 1990-12-12 EP disclosed
EP-0402004-A1 Laminates of metal and polyester film CarnaudMetalbox plc (GB) 1990-12-12 EP disclosed
EP-0367493-A2 Process for coating the inside surface of a metallic can with a water-base paint MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-05-09 EP disclosed
US-4264667-A Polyester film TOYO BOSEKI KABUSHIKI KAISHA (JP) 1981-04-28 US disclosed
US-3993843-A Aqueous dispersion of aromatic polysulfone resin with perfluorocarbon resin, and coated articles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-23 US disclosed
US-3948839-A CROSSLINKED NYLON OR POLYESTER UNIFILM CORPORATION (US) 1976-04-06 US disclosed