⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588374 | 0.79 | — | — | |
| SCHEMBL10673507 | 0.77 | — | — | |
| SCHEMBL27650784 | 0.74 | FDPS (0.33) | — | |
| SCHEMBL29227586 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL21518273 | 0.72 | ALOX15 (0.36) | — | |
| SCHEMBL21731861 | 0.72 | — | — | |
| SCHEMBL93241 | 0.72 | — | — | |
| SCHEMBL16599954 | 0.72 | — | — | |
| Ethylene Glycol Diformate SCHEMBL827902 | 0.71 | — | — | |
| SCHEMBL12329354 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | claimed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | claimed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | claimed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | claimed |
| EP-0555175-A1 | Biaryl substituted 4-amino-butyric acid amides | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | claimed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | claimed |
| EP-1036564-B1 | Thyromimetic antiobesity agents | PFIZER PROD INC (US) | 2004-11-17 | — | — | EP | disclosed |
| US-20030166731-A1 | Method of treating hair loss using diphenylether derivatives | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2003-09-04 | — | — | US | disclosed |
| US-6555578-B2 | Kits; containing a compound containing an oxamic acid group | PFIZER INC. | 2003-04-29 | — | — | US | disclosed |
| US-6525094-B1 | Topical application of compound that interacts strongly with thyroid hormone receptors but sparingly with heart selective hormone receptors | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2003-02-25 | — | — | US | disclosed |
| US-20020035153-A1 | Thyromimetic antiobesity agents | CORNELIUS PETER (US) | 2002-03-21 | — | — | US | disclosed |
| EP-1185230-A1 | METHOD OF TREATING HAIR LOSS USING DIPHENYLETHER DERIVATIVES | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2002-03-13 | — | — | EP | disclosed |
| US-5244889-A | Treatment of cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0555175-A1 | Biaryl substituted 4-amino-butyric acid amides | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | disclosed |
| US-5217996-A | Endopeptidase inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0544620-A1 | Macrocyclic lactams as inhibitors of atrial natriuretic factors (ANF)-degrading neutral endopeptidase (NEP) | CIBA-GEIGY AG (CH) | 1993-06-02 | — | — | EP | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |