Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904033 | 0.76 | SMN1; SMN2 (0.65) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11350463 | 0.74 | L3MBTL1 (0.62) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL48394 | 0.74 | MAPT (0.66) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL19994395 | 0.74 | MAPT (0.66) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL664795 | 0.73 | L3MBTL1 (0.61) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL1938172 | 0.73 | SMN1; SMN2 (0.62) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL13211468 | 0.73 | L3MBTL1 (0.61) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL13681839 | 0.73 | L3MBTL1 (0.61) | L3MBTL1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL12743239 | 0.73 | ALDH1A1 (0.38) | GRM5SMN1; SMN2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11645464 | 0.72 | CYP1A2 (0.44) | L3MBTL1GRM5KMT2ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168642-B2 | Dihydropyrimidine compounds and their uses in preparation of medicaments for treating and preventing antiviral diseases | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2012-05-01 | — | — | US | disclosed |
| EP-2039686-B1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN PREPARATION OF MEDICAMENTS FOR TREATING AND PREVENTING ANTIVIRAL DISEASES | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO LTD (CN) | 2012-02-29 | — | — | EP | disclosed |
| US-20100087448-A1 | Dihydropyrimidine Compounds and Their Uses in Preparation of Medicaments for Treating and Preventing Antiviral Diseases | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2010-04-08 | — | — | US | disclosed |
| EP-2039686-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN PREPARATION OF MEDICAMENTS FOR TREATING AND PREVENTING ANTIVIRAL DISEASES | Beijing Molecule Science and Technology Co., Ltd. (CN) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087448-A1 | Dihydropyrimidine Compounds and Their Uses in Preparation of Medicaments for Treating and Preventing Antiviral Diseases | DPYD, HPRT1, DHX15 | L3MBTL1 3723/4885GRM5 3304/4885KMT2A 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.