SCHEMBL6899407

SCHEMBL6899407

OC(F)(F)C(O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.39
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197104 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8613098 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8615317 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8613264 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL197971 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL6258951 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8090318 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8614288 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL345851 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1
SCHEMBL8613060 1.00 LMNA (0.40) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021044-A1 POROUS HYDROGEL MICROSPHERES AND PREPARATION METHODS THEREOF SICHUAN CELL TISSUE BANK ENGINEERING TECHNOLOGY CO., LTD. (CN) 2026-01-22 US claimed
US-20260021044-A1 POROUS HYDROGEL MICROSPHERES AND PREPARATION METHODS THEREOF SICHUAN CELL TISSUE BANK ENGINEERING TECHNOLOGY CO., LTD. (CN) 2026-01-22 US disclosed
US-6825377-B1 CATALYTIC OXIDATION USING OXYGEN OR GAS MIXTURE IN PRESENCE OF OSMIUM, RUTHENIUM, OR MANGANESE COMPOUND IN WATER; ADDING AMINE FOR CATALYST SELECTIVITY BAYER AKTIENGESELLSCHAFT (DE) 2004-11-30 US disclosed
US-6472570-B1 Method for the asymmetric dihydroxylation of olefins, using osmium catalysts BAYER AKTIENGESELLSCHAFT (DE) 2002-10-29 US disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
EP-0540976-A1 Use of polyisocyanate solutions for the impregnation of mineral substrates BAYER AG (DE) 1993-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021044-A1 POROUS HYDROGEL MICROSPHERES AND PREPARATION METHODS THEREOF MKI67, PCNA, STUB1 LMNA 253/4885THRB 3967/4885CA2 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.