Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056986 | 0.92 | CACNA1H (0.63) | CACNA1HCACNA1BGAAMCHR1RAB9A | |
| SCHEMBL6897990 | 0.90 | MCHR1 (0.53) | CACNA1HCACNA1BGAAMCHR1RAB9A | |
| SCHEMBL6898486 | 0.87 | GAA (0.58) | CACNA1HCACNA1BGAAMCHR1RAB9A | |
| SCHEMBL6900340 | 0.84 | MCHR1 (0.68) | CACNA1HCACNA1BGAAMCHR1RAB9A | |
| SCHEMBL6899776 | 0.83 | THRB (0.61) | MCHR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7051105 | 0.83 | MEN1 (0.58) | CACNA1HCACNA1BMCHR1RAB9AMEN1 | |
| SCHEMBL3500701 | 0.82 | GAA (0.60) | CACNA1HCACNA1BGAAMCHR1RAB9A | |
| SCHEMBL6895401 | 0.81 | MCHR1 (0.70) | MCHR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL5936600 | 0.79 | CACNA1H (0.70) | CACNA1HCACNA1BGAARAB9AMEN1 | |
| SCHEMBL6898504 | 0.79 | GAA (0.56) | CACNA1HCACNA1BGAAMCHR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |